ABSTRACT
Outbreak of Covid-19 pandemic shook the world. Life came to a near standstill because of the pandemic. Each and every phase of everyone's life has been affected by the virus in one way or another. The phenomenon of migration which has a close relation with the spread of virus was also deeply affected by the outbreak of Covid- 19. The present paper provides a deep insight on how international student mobility from Punjab was affected because of Covid-19 pandemic. The pandemic affected the lives of many individuals and puts a break on the flight of dreams of many students in Punjab to go abroad for higher education. It is also anticipated that mass exodus of students to foreign land may be seen in the post pandemic world.
ABSTRACT
Covid-19 has affected the global population and brought normal human life to a standstill. There are currently no approved treatments for COVID-19, and researchers across the globe are working furiously to find a potential treatment for COVID-19. In the present review paper, we have analyzed the research characteristics and trends of COVID-19 clinical trials by processing and analyzing the relevant data from the WHO International Clinical Trials Registry Platform (ICTRP), Chinese Clinical Trial Registration Center database, and ClinicalTrials.gov website to provide researchers with an overall summary and insight of the current clinical trials for the prevention and treatment of COVID-19.
ABSTRACT
In the crisis period due to global health threat caused by COVID-19 pandemic in the last few months of 2020 and the imposed lockdown in India, mass media played a very crucial role to make the countless mass of recipients aware and conscious about what is happening throughout the world. The study aims to find out informative role of mass media over traditional media in creating awareness about agriculture during the pandemic and exposure to mass media by the Santals of Birbhum District, West Bengal. Telephonic questionnaire through mobile contact was applied to collect quantitative data from 100 Santal agricultural labours of both local and migrant (50 male, 50 female) from 4 selected villages. It was observed that, though availability of mass media with the Santals was limited, however, their accessibility to mass media like TV or mobile phone was found somewhat better in creating awareness and consciousness about agricultural activities during the pandemic period among the Santals. Mean value of agricultural information consumption based on mass media of female Santals (X2= 109.43) was better than the male Santals (X1= 106.18). 't' value, which was 3.40, much more than the significant level, indicated that the agricultural information consumption based on mass media of female Santals is greater than that of male Santals in COVID-19 pandemic. Study finally suggested for balanced combination of traditional media and mass media in developing more awareness and consciousness among the Santals in the epidemic and pandemic period.
ABSTRACT
Sulfur-containing indoles are widely studied against different biological targets. Among several potential drug candidates, seven molecules of this class are in the current market and a few of them are either in pipeline or in different stages of clinical trials. Particularly, arylthioindoles or indolylarylsulfones (IAS) received great attention by medicinal chemists due to their pharmokinetic profiles and wide spectrum of biological activities like antiviral, anticancer, cardiovascular, and antibacterial properties. This review summarizes the developmental process, synthesis and structure activity relationship (SAR) around arylthioindole/indolylaryl sulfone scaffolds for antiviral/anti-HIV non-nucleoside reverse transcriptase inhibitor (NNRTIs) activities. It also offers perspective for further development of 3-indolylarylsulfones as an anti-viral agent including their potential against novel COVID-19 infection. © 2022 Wiley-VCH GmbH
ABSTRACT
Pandemics bear unique challenges which require a fast response from health system on many aspects ranging from prevention to management through rapid diagnostic modalities, drug/vaccine discovery, and health resource allocation and planning management. However, in low resource settings, the mismatch between demand & supply of health services and inadequate knowledge about the course of pandemic results in failure in management of pandemic & resulted in loss of human lives. However, due to discovery of the latest technologies like artificial intelligence (AI), the pandemic is often managed from prevention to management level in a predictive manner. AI is increasingly being studied as a useful gizmo to assist in preventing pandemic and managing existing crisis in a timely manner. However, while AI has been proved to be useful in its ability to assist halting the rapid spread or contamination of disease during a pandemic, there exist few ethical and legal issues that have gotten to be taken care of before it is to be utilized in a mass scale.
ABSTRACT
Introduction: Data on COVID-19 transmission, manifestations and outcome for the neonatal population is scarce, particularly from developing country settings. Objectives: To assess the transmission risk of SARS-CoV-2 in the mother-infant dyad and to describe the clinical profile of neonates born to COVID-19 positive mothers in a tertiary care centre in Northern India. Method: An observational cohort study was conducted in the neonatal COVID-19 unit of All India Institute of Medical Sciences Patna, India. All neonates delivered by COVID-19 positive mothers at this hospital were admitted. During the pandemic, admissions were also allowed for out-born neonates positive for SARS-CoV-2. COVID-19 RT-PCR on nasopharyngeal swab of neonate at 24 and 48-72 hours was the primary outcome variable. Clinicolaboratory variables were collected during the hospital stay and follow up. An inferential analysis was done using SPSS version 22.0. Results: Fifty-one out of 145 (142 delivered at our institute and 3 at other institutes) pregnant women tested positive for COVID-19. Two in-born neonates and two out-born neonates also tested positive. They had a significantly higher respiratory rate (p=0.0006) as compared to COVID-19 negative new-borns. COVID-19 RT-PCR done on breast milk samples of twenty-five mothers, tested negative.One inborn COVID-19 negative neonate born to a COVID-19 positive mother died of severe birth asphyxia due to meconium-stained liquor. One inborn COVID-19 negative neonate born to a COVID-19 positive mother required 27 days of ventilator support due to meconium stained liquor. All other neonates, except two with risk factors, remained clinically stable requiring no specific treatment during hospital stay and follow-up. Conclusions: With standard infection prevention and control practices, potential of infection transmission in neonates exists though they had less severe disease and needed no specific treatment except supportive care. © 2021,Sri Lanka Journal of Child Health. All rights reserved.